Search results for "Excessive sleep"

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Heritability and genome-wide association analyses of sleep duration in children: The EAGLE Consortium.

2016

STUDY OBJECTIVES: Low or excessive sleep duration has been associated with multiple outcomes, but the biology behind these associations remains elusive. Specifically, genetic studies in children are scarce. In this study, we aimed to: (1) estimate the proportion of genetic variance of sleep duration in children attributed to common single nucleotide polymorphisms (SNPs), (2) identify novel SNPs associated with sleep duration in children, and (3) investigate the genetic overlap of sleep duration in children and related metabolic and psychiatric traits.METHODS: We performed a population-based molecular genetic study, using data form the EArly Genetics and Life course Epidemiology (EAGLE) Cons…

Male0301 basic medicineTime FactorsAdolescentSleep Duration/Sleep QualityPopulationSingle-nucleotide polymorphismGenome-wide association studyPolymorphism Single NucleotideWhite PeopleSNP heritabilityCohort Studies03 medical and health sciencesQuantitative Trait Heritable0302 clinical medicine030225 pediatricsPhysiology (medical)Genetic variationHumansSNPMedicineLongitudinal StudiesChildeducationeducation.field_of_studybusiness.industryExcessive sleepHeritabilitygenome-wide association study (GWAS)medicine.disease3. Good healthpathway analysismeta-analysis030104 developmental biologyDiabetes Mellitus Type 2Child PreschoolMeta-analysisFemaleNeurology (clinical)Sleepbusinesschildhood sleep durationSnp Heritability ; Genome-wide Association Study (gwas) ; Meta-analysis ; Childhood Sleep Duration ; Pathway AnalysisGenome-Wide Association StudyDemography
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Maternal sleep duration and neonate birth weight: A population-based cohort study.

2021

Objective Sleep duration is an important health indicator. Our aim was to investigate the association between maternal sleep duration and infant birthweight. Methods The study included 2,536 mother-infant pairs of a Spanish birth cohort (2004-2006, INMA project). The exposures were questionnaire-based measures of sleep duration before and during pregnancy. The primary outcome was infant birthweight score (g) standardized to 40 weeks of gestation. Results In women sleeping less than 7 hours per day before pregnancy, each additional hour of sleep increased birthweight score by 44.7 g (p = 0.049) in the minimally-adjusted model, although findings were not statistically significant after consid…

medicine.medical_specialtyBirth weightMothersAffect (psychology)Cohort Studies03 medical and health sciences0302 clinical medicinePregnancymedicineBirth WeightHumans030212 general & internal medicinePregnancy030219 obstetrics & reproductive medicineObstetricsbusiness.industryConfoundingExcessive sleepInfant NewbornObstetrics and GynecologyGeneral Medicinemedicine.diseaseSleep in non-human animalsDuration (music)Pregnancy Trimester SecondGestationFemalebusinessSleepInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and ObstetricsREFERENCES
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